Friday, March 11, 2011

Anatomy of the cat


Domestic cats are similar in size to the other members of the genus Felis, typically weighing between 4 kilograms (8 lb 13 oz) and 5 kilograms (11 lb 0 oz). However, some breeds, such as the Maine Coon, can exceed 11 kilograms (25 lb). Conversely, very small cats (less than 1.8 kilograms (3 lb 15 oz)) have been reported. The world record for the largest cat is 21.297 kilograms (46 lb 15.2 oz). The smallest adult cat ever officially recorded weighed around 1.36 kilograms (3 lb). Cats average about 23–25 centimeters (9–10 in) in height and 46 centimeters (18.1 in) in head/body length (males being larger than females), with tails averaging 30 centimeters (11.8 in) in length.
Cats have 7 cervical vertebrae like almost all mammals, 13 thoracic vertebrae (humans have 12), 7 lumbar vertebrae (humans have 5), 3 sacral vertebrae like most mammals (humans have 5 because of their bipedal posture), and a variable number of caudal vertebrae in the tail (humans retain 3 to 5 caudal vertebrae, fused into an internal coccyx). The extra lumbar and thoracic vertebrae account for the cat's spinal mobility and flexibility. Attached to the spine are 13 ribs, the shoulder, and the pelvis. Unlike human arms, cat forelimbs are attached to the shoulder by free-floating clavicle bones, which allow them to pass their body through any space into which they can fit their heads.

Cats, like dogs, are digitigrades. They walk directly on their toes, with the bones of their feet making up the lower part of the visible leg.Cats are capable of walking very precisely, because like all felines they directly register; that is, they place each hind paw (almost) directly in the print of the corresponding forepaw, minimizing noise and visible tracks. This also provides sure footing for their hind paws when they navigate rough terrain. Unlike most mammals, when cats walk, they use a "pacing" gait; that is, they move the two legs on one side of the body before the legs on the other side. This trait is shared with camels and giraffes. As a walk speeds up into a trot, a cat's gait will change to be a "diagonal" gait, similar to other mammals: the diagonally opposite hind and forelegs will move simultaneously.The cat skull is unusual among mammals in having very large eye sockets and a powerful and specialized jaw.[51] Within the jaw, cats have teeth adapted for killing prey and tearing meat. When it overpowers its prey, a cat delivers a lethal neck bite with its two long canine teeth, inserting them between two of the prey's vertebrae and severing its spinal cord, causing irreversible paralysis and death. Compared to other felines, domestic cats have narrowly spaced canine teeth; which is an adaptation to their preferred prey of small rodents, which have small vertebrae. The premolar and first molar together compose the carnassial pair on each side of the mouth, which efficiently shears meat into small pieces, like a pair of scissors. These are vital in feeding, since cats' small molars cannot chew food effectively.
Like almost all members of the Felidae family, cats have protractable claws. In their normal, relaxed position the claws are sheathed with the skin and fur around the toe pads. This keeps the claws sharp by preventing wear from contact with the ground and allows the silent stalking of prey. The claws on the forefeet are typically sharper than those on the hind feet. Cats can voluntarily extend their claws on one or more paws. They may extend their claws in hunting or self-defense, climbing, "kneading", or for extra traction on soft surfaces. Most cats have five claws on their front paws, and four on their rear paws. The fifth front claw (the dewclaw) is proximal to the other claws. More proximally, there is a protrusion which appears to be a sixth "finger". This special feature of the front paws, on the inside of the wrists, is the carpal pad, also found on the paws of big cats and dogs. It has no function in normal walking, but is thought to be an anti-skidding device used while jumping. Some breeds of cats are prone to polydactylyism, and may have eight or even ten toes. These are particularly common along the North-East coast of North America.

The Cat genetics


The domesticated cat and its closest wild ancestor are both diploid organisms that possess 38 chromosomes and roughly 20,000 genes. About 250 heritable genetic disorders have been identified in cats, many similar to human inborn errors. The high level of similarity among the metabolisms of mammals allows many of these feline diseases to be diagnosed using genetic tests that were originally developed for use in humans, as well as the use of cats in the study of the human diseases.
An interesting example of a mutation that is shared among all felines, including the big cats, is a mutant chemosensor in their taste buds that prevents them from tasting sweetness, which may explain their indifference to fruits, berries, and other sugary foods. In some breeds of catscongenital deafness is very common, with most white cats (but not albinos) being affected, particularly if they also have blue eyes. The genes responsible for this defect are unknown, but the disease is studied in the hope that it may shed light on the causes of hereditary deafness in humans.
Since a large variety of coat patterns exist within the various cat breeds, the cat is an excellent animal to study the coat genetics of hair growth and coloration. Several genes interact to produce cats' hair color and coat patterns. Different combinations of these genes give different phenotypes. For example, the enzyme tyrosinase is needed to produce the dark pigment melanin and Burmese cats have a mutant form that is only active at low temperatures, resulting in color appearing only on the cooler ears, tail and paws. A completely inactive gene for tyrosinase is found in albino cats, which therefore lack all pigment. Hair length is determined by the gene for fibroblast growth factor 5, with inactive copies of this gene causing long hair.
The Cat Genome Project, sponsored by the Laboratory of Genomic Diversity at the U.S. National Cancer Institute Frederick Cancer Research and Development Center in Frederick, Maryland, aims to help the development of the cat as an animal model for human hereditary and infectious diseases, as well as contributing to the understanding of the evolution of mammals. This effort led to the publication in 2007 of an initial draft of the genome of an Abyssinian cat called Cinnamon. The existence of a draft genome has led to the discovery of several cat disease genes, and even allowed the development of cat genetic fingerprinting for use in forensics.